Does diffusion-tensor MR imaging provide accurate tracing of specific white matter tracts that correspond to actual anatomic and functional units in the central nervous system?

Publication/Presentation Date

12-1-2008

Abstract

By using healthy common marmoset monkeys, Yamada et al traced the retinogeniculate pathways with ultra high-spatial-resolution manganese-enhanced magnetic resonance (MR) imaging and diffusion-tensor imaging at 7 T. Both methods were compared with morphologic findings described in published histopathologic studies. Both methods provided identical tracing of the optic nerve, optic chiasm, and optic tracts to the level of the lateral geniculate nucleus (LGN), faithfully reproducing the crossing of the nasal portion of the optic nerve at the level of the chiasm into the contralateral optic tract. This study strongly suggests that diffusion-tensor imaging, a noninvasive method that can be used in human research and clinical practice, has the potential to provide accurate tracing of specific white matter tracts that correspond to actual anatomic and functional units in the central nervous system.

Volume

249

Issue

3

First Page

725

Last Page

727

ISSN

1527-1315

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

19011176

Department(s)

Administration and Leadership

Document Type

Article

Share

COinS