Extraventricular neurocytoma and ganglioneurocytoma: advanced MR imaging, histopathological, and chromosomal findings.

Authors

• Seyed Ali Nabavizadeh
• Sanjeev Chawla
• Jennifer Baccon
• Paul J Zhang
• Harish Poptani
• Elias R Melhem
• Arastoo Vossough

Publication/Presentation Date

1-1-2014

Abstract

Extraventricular neurocytoma and ganglioneurocytoma are rare intra-axial brain neoplasms that are now recognized as distinct entities in the 2007 WHO classification of brain tumors. We describe the conventional MR imaging, perfusion MRI, proton MR spectroscopy (1H MRS), histopathology, immunohistochemistry, and chromosomal analysis in two cases of these tumors, with some features which have not been previously well described. Both tumor types demonstrated markedly elevated cerebral blood volume on perfusion MRI and had 1p19q chromosomal codeletions. Both tumor types showed an elevated Cho/Cr ratio, but extraventricular ganglioneurocytoma showed a preserved NAA/Cr ratio. These tumors should be considered in the differential diagnosis of intra-axial brain tumors.

Volume

24

Issue

6

First Page

613

Last Page

616

ISSN

1552-6569

Published In/Presented At

Nabavizadeh, S. A., Chawla, S., Baccon, J., Zhang, P. J., Poptani, H., Melhem, E. R., & Vossough, A. (2014). Extraventricular neurocytoma and ganglioneurocytoma: advanced MR imaging, histopathological, and chromosomal findings. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 24(6), 613–616. https://doi.org/10.1111/jon.12081

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

24787229

Department(s)

Administration and Leadership

Document Type

Article