Proton magnetic resonance spectroscopy (H-MRS) studies of schizophrenia.
Publication/Presentation Date
4-1-2001
Abstract
Proton magnetic resonance spectroscopy ((1)H-MRS) is a noninvasive technique that can quantify biochemical compounds in the brain. (1)H-MRS has been used to investigate neural structures implicated in the pathology of schizophrenia. The majority of research has revealed reduced N-acetylaspartate (NAA), an index of neuronal integrity, in frontal and temporal regions of medicated and chronically ill patients with schizophrenia. This review summarizes basic principles of (1)H-MRS, studies of frontal, temporal, subcortical, and cerebellar regions in schizophrenia. Technical and study design limitations are also discussed.
Volume
6
Issue
2
First Page
121
Last Page
130
ISSN
1084-3612
Published In/Presented At
Rowland, L., Bustillo, J. R., & Lauriello, J. (2001). Proton magnetic resonance spectroscopy (H-MRS) studies of schizophrenia. Seminars in clinical neuropsychiatry, 6(2), 121–130. https://doi.org/10.1053/scnp.2001.21838
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
11296312
Department(s)
Administration and Leadership
Document Type
Article