Can structural neuroimaging be used to define phenotypes and course of schizophrenia?
Publication/Presentation Date
9-1-2012
Abstract
This article examines whether structural neuroimaging measures have been found to predict outcome in schizophrenia and whether changes in neuroimaging measures have been found to correlate with poor outcome in the disorder. Overall, there is little compelling evidence that structural neuroimaging measures in either first-episode or chronic patients predict future outcome. Progressive brain changes might reflect a neuroimaging phenotype associated with a worse course of the disorder. At the same time, there are many fruitful avenues that future research could take in an attempt to better predict future outcome or to identify specific imaging phenotypes associated with outcome.
Volume
35
Issue
3
First Page
633
Last Page
644
ISSN
1558-3147
Published In/Presented At
Kerns, J. G., & Lauriello, J. (2012). Can structural neuroimaging be used to define phenotypes and course of schizophrenia?. The Psychiatric clinics of North America, 35(3), 633–644. https://doi.org/10.1016/j.psc.2012.06.005
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
22929870
Department(s)
Administration and Leadership
Document Type
Article