Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil.
Publication/Presentation Date
4-1-2002
Abstract
PURPOSE: To report the effect of 5-fluorouracil on the outcome of a single case of epithelial ingrowth secondary to a wound leak after a complicated penetrating keratoplasty.
DESIGN: Case report.
METHODS: A 44-year-old man with extensive epithelial ingrowth after trauma and a penetrating keratoplasty received a fluid-gas exchange followed by two injections of 500 microg of 5-fluorouracil into the anterior chamber.
RESULTS: Two weeks after receiving the 5-fluorouracil injections, complete disappearance of the epithelial ingrowth from the anterior chamber occurred. No evidence of recurrence was detectable at 5 months.
CONCLUSION: Use of 5-fluorouracil is a potentially effective treatment of epithelial ingrowth, particularly in eyes with extensive involvement, in which the risks of traditional ablative therapeutic modalities are considerable.
Volume
133
Issue
4
First Page
562
Last Page
564
ISSN
0002-9394
Published In/Presented At
Lai, M. M., & Haller, J. A. (2002). Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil. American journal of ophthalmology, 133(4), 562–564. https://doi.org/10.1016/s0002-9394(01)01419-2
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
11931795
Department(s)
Administration and Leadership
Document Type
Article