Effect of edema on the post-implant dosimetry of an I-125 prostate implant: a case study.
Publication/Presentation Date
5-1-1997
Abstract
PURPOSE: To investigate the effect of post-implant edema on the CT-based calculation of the total dose delivered by an I-125 prostate implant.
MATERIALS AND METHODS: CT scans of a transperineal I-125 prostate implant were obtained 1 and 39-days post-implant. Changes in the prostate dimensions were determined from changes in the spatial distribution of the I-125 seeds. The total dose delivered to the target volume was computed from each CT scan, and the results compared.
RESULTS: The volume of the prostate decreased by approximately 17% during the 38-day interval between the first and second CT scans. As a result, the radiation dose computed from the second CT scan was 13% higher.
CONCLUSION: Post-implant edema can cause a significant underestimation of the radiation dose delivered by an I-125 prostate implant. Similar analysis should be carried out among a larger cohort of patients to confirm or refute these observations.
Volume
38
Issue
2
First Page
335
Last Page
339
ISSN
0360-3016
Published In/Presented At
Waterman, F. M., Yue, N., Reisinger, S., Dicker, A., & Corn, B. W. (1997). Effect of edema on the post-implant dosimetry of an I-125 prostate implant: a case study. International journal of radiation oncology, biology, physics, 38(2), 335–339. https://doi.org/10.1016/s0360-3016(97)00114-4
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
9226320
Department(s)
Administration and Leadership
Document Type
Article