Woven EndoBridge Device embolization versus microsurgical clipping of intracranial aneurysms: A systematic review of literature.
Publication/Presentation Date
2-1-2025
Abstract
BACKGROUND AND OBJECTIVES: The WovenEndoBridge Device (WEB) is an intrasaccular flow disruptor that has demonstrated satisfactory results with treating intracranial aneurysms of varying size and morphology. Our systematic review of literature compares WEB embolization to microsurgical clipping.
METHODS: PubMed and Scopus were searched from inception until October 9, 2024. Articles that reported comparative outcomes for WEB embolization versus microsurgical clipping of intracranial aneurysms were included. A qualitative assessment was performed using the ROBINS-I tool.
RESULTS: 3074 abstracts and 8 full-text articles were reviewed. 3 articles describing outcomes in 243 patients who underwent microsurgical clipping and 269 patients who underwent WEB embolization met criteria for inclusion. Microsurgical clipping was associated with higher rates of aneurysm occlusion and lower rates of re-treatment compared to WEB embolization. Rates of peri-procedural complications were higher with microsurgical clipping. Functional outcome was comparable across cohorts.
CONCLUSION: Our review identified higher rates of angiographic occlusion, greater technical success, and lower rates of re-treatment with microsurgical clipping compared to WEB embolization. However, this was at the cost of increased peri-procedural complications. Further research is needed to help identify the optimal treatment modality for specific patient populations.
Volume
249
First Page
108773
Last Page
108773
ISSN
1872-6968
Published In/Presented At
Roy, J. M., Musmar, B., Patel, P., Katharine-Pontarelli, M., Atallah, E., Papadopoulos, E., Tjoumakaris, S. I., Gooch, M. R., Rosenwasser, R. H., & Jabbour, P. M. (2025). Woven EndoBridge Device embolization versus microsurgical clipping of intracranial aneurysms: A systematic review of literature. Clinical neurology and neurosurgery, 249, 108773. https://doi.org/10.1016/j.clineuro.2025.108773
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
39919402
Department(s)
Administration and Leadership
Document Type
Article