Improving tumor response to radiotherapy by targeting angiogenesis signaling pathways.
Publication/Presentation Date
10-1-2004
Abstract
Radiotherapy is one of the most widely used treatments for cancer; however, the development of tumor radioresistance is an ongoing problem. Agents that target tumor angiogenesis are being used in combination with radiotherapy to improve the therapeutic index without a clear understanding of how these agents may affect radiosensitization. This article discusses recently published studies that may shed some light on the underlying signaling mechanisms that are involved in the interactions of antiangiogenic agents with ionizing radiation.
Volume
18
Issue
5
First Page
1039
Last Page
1057
ISSN
0889-8588
Published In/Presented At
Wachsberger, P., Burd, R., & Dicker, A. P. (2004). Improving tumor response to radiotherapy by targeting angiogenesis signaling pathways. Hematology/oncology clinics of North America, 18(5), 1039–viii. https://doi.org/10.1016/j.hoc.2004.06.007
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
15474334
Department(s)
Administration and Leadership
Document Type
Article