Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma.
Publication/Presentation Date
4-1-2025
Abstract
Chronic subdural hematoma (cSDH) presents a multifaceted challenge in contemporary neurological practice, necessitating innovative therapeutic strategies. This comprehensive review explores the convergence of two promising interventions: statins and middle meningeal artery (MMA) Embolization. With cSDH incidence on the rise, particularly among the aging population and those with long-term anticoagulant usage, the traditional surgical avenues face limitations in recurrence rates and associated risk factors. Statins, heralded for their anti-inflammatory, vasculogenic, and angiogenic properties, are emerging as potential allies in cSDH management. Concurrently, MMA embolization offers a nuanced approach to target the neomembrane's blood supply, with evidence supporting its efficacy and safety. However, the synthesis of MMA embolization with statins remains relatively unexplored, presenting a complex interplay between inflammation modulation and blood supply interruption.
Volume
69
Issue
2
First Page
218
Last Page
224
ISSN
1827-1855
Published In/Presented At
Musmar, B., Roy, J. M., Spellicy, S., Tjoumakaris, S. I., Gooch, M. R., Rosenwasser, R. H., Hasan, D., & Jabbour, P. (2025). Statins and middle meningeal artery embolization: a literature review in the treatment of chronic subdural hematoma. Journal of neurosurgical sciences, 69(2), 218–224. https://doi.org/10.23736/S0390-5616.25.06426-4
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
40340286
Department(s)
Administration and Leadership
Document Type
Article