Correlation of Computed Tomography Angiography to Digital Subtraction Angiography in Carotid Stenosis with Real-World Assessment of Overestimation of Carotid Stenosis on Computed Tomography Angiography.
Publication/Presentation Date
9-1-2024
Abstract
OBJECTIVE: Computed tomography angiography (CTA) is a well-established diagnostic modality for carotid stenosis. However, false-positive CTA results may expose patients to unnecessary procedural complications in cases where surgical intervention is not warranted. We aim to assess the correlation of CTA to digital subtraction angiography (DSA) in carotid stenosis and characterize patients who were referred for intervention based on CTA and did not require it based on DSA.
METHODS: We retrospectively reviewed 186 patients who underwent carotid angioplasty and stenting following preprocedural CTA at our institution from April 2017 to December 2022.
RESULTS: Twenty-one of 186 patients (11.2%) were found to have < 50% carotid stenosis on DSA (discordant group). Severe plaque calcification on CTA was associated with a discordant degree of stenosis on DSA (LR+=7.4). Among 186 patients, agreement between the percentage of stenosis from CTA and DSA was weak-moderate (r
CONCLUSIONS: In patients with stenosis found on CTA, over 88% also had stenosis on DSA, with this positive predictive value in line with previous studies. The percent-stenosis value from CTA and DSA was weakly correlated but does not affect the overall clinical judgement of stenosis. Severe calcification found on CTA may potentially indicate nonstenosis on DSA.
Volume
189
First Page
452
Last Page
452
ISSN
1878-8769
Published In/Presented At
Roy, J. M., Abbas, R., Chong, W., Muharemmi, E., Hai, Y., Morse, C., El Naamani, K., Atallah, E., Herial, N. A., Tjoumakaris, S., Gooch, M. R., Rosenwasser, R. H., Flanders, A., & Jabbour, P. (2024). Correlation of Computed Tomography Angiography to Digital Subtraction Angiography in Carotid Stenosis with Real-World Assessment of Overestimation of Carotid Stenosis on Computed Tomography Angiography. World neurosurgery, 189, e452–e458. https://doi.org/10.1016/j.wneu.2024.06.084
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
38906473
Department(s)
Administration and Leadership
Document Type
Article