Single institution implementation of permanent

Authors

• Voichita Bar-Ad
• Emily Hubley
• Adam Luginbuhl
• David Cognetti
• Joseph Curry
• Amy S Harrison
• Jennifer M Johnson
• James Keller
• Cheng Peng
• David To
• Laura Doyle

Publication/Presentation Date

6-1-2019

Abstract

PURPOSE: Permanent interstitial brachytherapy is an appealing treatment modality for patients with locoregional recurrent, resectable head and neck carcinoma (HNC), having previously received radiation. Cesium-131 (

MATERIAL AND METHODS: Fifteen patients receiving

RESULTS: Tumor volumes were contoured on the available preoperative PET/CT scans and a pre-implant treatment plan was created using uniform source strength and uniform 1 cm seed spacing. Implants were performed intraoperatively, following tumor resection. In five of the fifteen cases, intraoperative findings necessitated a change from the planned number of seeds and recalculation of the pre-implant plan. The average prescription dose was 56.1 ±6.6 Gy (range, 40-60 Gy). The average seed strength used was 2.2 ±0.2 U (3.5 ±0.3 mCi). Patients returned to a recovery room on a standard surgical floor and remained inpatients, without radiation safety restrictions, based on standard surgical recovery protocols. A post-implant treatment plan was generated based on immediate post-operative CT imaging to verify the seed distribution and confirm delivery of the prescription dose. Patients were provided educational information regarding radiation safety recommendations.

CONCLUSIONS: Cesium-131 interstitial brachytherapy is feasible and does not pose major radiation safety concerns; it should be considered as a treatment option for previously irradiated patients with recurrent, resectable HNC.

Volume

11

Issue

3

First Page

227

Last Page

234

ISSN

1689-832X

Published In/Presented At

Bar-Ad, V., Hubley, E., Luginbuhl, A., Cognetti, D., Curry, J., Harrison, A. S., Johnson, J. M., Keller, J., Peng, C., To, D., & Doyle, L. (2019). Single institution implementation of permanent 131Cs interstitial brachytherapy for previously irradiated patients with resectable recurrent head and neck carcinoma. Journal of contemporary brachytherapy, 11(3), 227–234. https://doi.org/10.5114/jcb.2019.85778

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

31435429

Department(s)

Administration and Leadership

Document Type

Article