Evaluation of oncologic outcomes in head and neck cancer patients ≥80 years old based on adherence to NCCN guideline for postoperative adjuvant treatment.
Publication/Presentation Date
12-1-2019
Abstract
BACKGROUND: There is a paucity of literature characterizing outcomes in older adult patients with head and neck cancer (HNC). This study aims to describe patients from this group, their adherence to National Comprehensive Cancer Network (NCCN) adjuvant treatment guidelines, and the impact of guideline adherence on overall survival (OS).
METHODS: In this retrospective cohort study, we reviewed all patients ≥80 years old with HNC who underwent surgery with curative intent from 2008 to 2016. Adherence to NCCN guidelines was determined in blinded fashion, and quality metrics and OS were compared.
RESULTS: One hundred fifty-nine patients met inclusion criteria. The majority of patients (n = 94, 59%) underwent treatment in accordance with NCCN recommendations while 65 (41%) deviated from NCCN guidelines. The two cohorts did not demonstrate a difference in 2-year OS (62% vs 66%, P = .50).
CONCLUSION: Older adult patient outcomes were not different when treatment deviated from NCCN guidelines.
Volume
41
Issue
12
First Page
4128
Last Page
4135
ISSN
1097-0347
Published In/Presented At
Roden, D., Daniels, K., Metkus, J., Goldman, R., Walsh, A., Johnson, J., Hamilton, J., Keane, W., Chapman, A., Bar-Ad, V., Sweeny, L., Curry, J., Cognetti, D., & Luginbuhl, A. (2019). Evaluation of oncologic outcomes in head and neck cancer patients ≥80 years old based on adherence to NCCN guideline for postoperative adjuvant treatment. Head & neck, 41(12), 4128–4135. https://doi.org/10.1002/hed.25950
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
31512807
Department(s)
Administration and Leadership
Document Type
Article