Concurrent patient-partner treatment in pregnancy: an alternative to expedited partner therapy?
Publication/Presentation Date
9-1-2012
Abstract
BACKGROUND: Concurrent patient-partner treatment (CPPT) is the provision of treatment to the index patient and their sexual partner(s) and appears to be an effective method of preventing repeat sexually transmitted infections. The objectives of the study were to determine whether CPPT reduces the prevalence of a positive test of cure (TOC) for chlamydia and/or gonorrhea infection in pregnant women.
METHODS: We conducted an observational cohort study of 241 pregnant women aged 15 to 40 years diagnosed with chlamydia and/or gonorrhea receiving prenatal care at an urban teaching hospital. Pregnant women and their sexual partner(s) received CPPT consisting of azithromycin and/or cefpodoxime for treatment of chlamydia and/or gonorrhea infection, respectively, or patient referral consisting of an antibiotic prescription to the pregnant woman and advice for partner screening and therapy. Odds ratios (ORs) and survival estimates were calculated by χ or Fisher exact test, multivariable logistic regression, and Kaplan-Meier.
RESULTS: Forty-five pregnant women with chlamydia and/or gonorrhea received CPPT and were less likely to have a positive TOC (OR = 0; P < 0.001) and repeat positive chlamydia infection (OR = 0; P = 0.12) compared with 196 women that were treated and counseled on the patient referral treatment strategy for their sexual partners. CPPT shortened the median time to cure (4.4 weeks, standard deviation = 2.3) versus standard patient referral (5.1 weeks, standard deviation = 5.2). There were no repeat positive chlamydia infections in the CPPT group compared with 19 (18.1%) in the patient referral group.
CONCLUSIONS: CPPT decreased the prevalence of a positive TOC for chlamydia infection among pregnant women.
Volume
39
Issue
9
First Page
665
Last Page
670
ISSN
1537-4521
Published In/Presented At
Mmeje, O., & Coleman, J. S. (2012). Concurrent patient-partner treatment in pregnancy: an alternative to expedited partner therapy?. Sexually transmitted diseases, 39(9), 665–670. https://doi.org/10.1097/OLQ.0b013e318259f5a4
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
22902661
Department(s)
Administration and Leadership
Document Type
Article