What's in the mix: phylogenetic classification of metagenome sequence samples.
Publication/Presentation Date
10-1-2007
Abstract
Metagenomics is a novel field which deals with the sequencing and study of microbial organisms or viruses isolated directly from a particular environment. This has already provided a wealth of information and new insights for the inhabitants of various environmental niches. For a given sample, one would like to determine the phylogenetic provenance of the obtained fragments, the relative abundance of its different members, their metabolic capabilities, and the functional properties of the community as a whole. To this end, computational analyses are becoming increasingly indispensable tools. In this review, we focus on the problem of determining the phylogenetic identity of the sample fragments, a procedure known as 'binning'. This step is essential for the reconstruction of the metabolic capabilities of individual organisms or phylogenetic clades of a community, and the study of their interactions.
Volume
10
Issue
5
First Page
499
Last Page
503
ISSN
1369-5274
Published In/Presented At
McHardy, A. C., & Rigoutsos, I. (2007). What's in the mix: phylogenetic classification of metagenome sequence samples. Current opinion in microbiology, 10(5), 499–503. https://doi.org/10.1016/j.mib.2007.08.004
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
17933580
Department(s)
Administration and Leadership
Document Type
Article