Treatment effects of N-acetyl cysteine on resting-state functional MRI and cognitive performance in patients with chronic mild traumatic brain injury: a longitudinal study.
Publication/Presentation Date
1-1-2024
Abstract
Mild traumatic brain injury (mTBI) is a significant public health concern, specially characterized by a complex pattern of abnormal neural activity and functional connectivity. It is often associated with a broad spectrum of short-term and long-term cognitive and behavioral symptoms including memory dysfunction, headache, and balance difficulties. Furthermore, there is evidence that oxidative stress significantly contributes to these symptoms and neurophysiological changes. The purpose of this study was to assess the effect of N-acetylcysteine (NAC) on brain function and chronic symptoms in mTBI patients. Fifty patients diagnosed with chronic mTBI participated in this study. They were categorized into two groups including controls (CN,
Volume
15
First Page
1282198
Last Page
1282198
ISSN
1664-2295
Published In/Presented At
Vedaei, F., Newberg, A. B., Alizadeh, M., Zabrecky, G., Navarreto, E., Hriso, C., Wintering, N., Mohamed, F. B., & Monti, D. (2024). Treatment effects of N-acetyl cysteine on resting-state functional MRI and cognitive performance in patients with chronic mild traumatic brain injury: a longitudinal study. Frontiers in neurology, 15, 1282198. https://doi.org/10.3389/fneur.2024.1282198
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
38299014
Department(s)
Administration and Leadership
Document Type
Article