Atrial natriuretic peptides: receptors and second messengers.

Publication/Presentation Date

1-1-1989

Abstract

Atrial natriuretic peptides appear to elicit their actions in some target tissues by binding to a novel cell-surface transmembrane protein which possesses both peptide binding and guanylate cyclase activities. Ligand binding stimulates enzyme activity to produce increased intracellular concentrations of cyclic GMP which, in turn, mediates the cell's physiological response.

Volume

10

Issue

1

First Page

16

Last Page

19

ISSN

0265-9247

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

2540738

Department(s)

Administration and Leadership

Document Type

Article

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