An Evidence-Based Consensus for the Use of Neurostimulation for the Treatment of Non-Surgical Low Back Pain: The NEURON Group.
Publication/Presentation Date
1-1-2025
Abstract
INTRODUCTION: The use of electrical neuromodulation has often been limited to those with previous back surgery, peripheral neuropathy, and complex regional pain syndrome. Many patients with severe intractable low back pain were thought to be candidates for spinal cord stimulation (SCS), dorsal root ganglion stimulation, or peripheral nerve stimulation but did not meet the criteria. Recently, additional high-level data has supported the use of SCS in non-surgical low back pain (NSLBP), and United States Food and Drug Administration approval has been granted. The American Society of Pain and Neuroscience (ASPN) executive committee realized an unmet need to develop criteria for patient selection for this specific patient population. This is a NEURON project (neuroscience, education, utilization, risk mitigation, optimal outcomes, and neuromodulation), a living guideline for evolving therapies and indications, and is focused on the use of neuraxial stimulation for the treatment of refractory pain.
METHODS: After board approval, the society accepted nominees for the project, with an emphasis on experience, publication, research, and diversity. The team created an outline for discussion, chose a grading system based on published guidelines, and created consensus points.
RESULTS: The evidence led to several consensus points to best guide patient selection based on the level of evidence and expert opinion. The results will lead to improved safety and efficacy in implanted patients, and to a new standard for best practices.
CONCLUSION: The selection of patients for implantation in those who have NSLBP should be based on published literature, best practice, and expert opinion. This NEURON project will allow for regular updates to create a living guideline that will allow for better assimilation of information to improve safety and efficacy going forward.
Volume
18
First Page
1247
Last Page
1274
ISSN
1178-7090
Published In/Presented At
Deer, T. R., Pope, J. E., Petersen, E. A., Abdallah, R. T., Amirdelfan, K., Azeem, N., Bansal, V., Barkoh, K., Chapman, K. B., Denis, D. R., Dorsi, M. J., Escobar, A., Falowski, S. M., Garcia, R. A., Hagedorn, J. M., Heros, R. D., James, W. S., Kalia, H., Lansford, T., Malinowski, M. N., … Sayed, D. (2025). An Evidence-Based Consensus for the Use of Neurostimulation for the Treatment of Non-Surgical Low Back Pain: The NEURON Group. Journal of pain research, 18, 1247–1274. https://doi.org/10.2147/JPR.S500342
Disciplines
Anesthesiology | Medicine and Health Sciences
PubMedID
40104824
Department(s)
Department of Anesthesiology
Document Type
Article
