A Rare Case of an Osteolytic Bone-infarct-associated Osteosarcoma: Case Report with Radiographic and Histopathologic Correlation, and Literature Review.
Publication/Presentation Date
6-11-2018
Abstract
Benign lesions such as Paget's disease of the bone, enchondroma, osteochondromas, chronic osteomyelitis/infections and bone infarcts may rarely undergo malignant degeneration/transformation into sarcomas. To date, only 14 prior bone infarct-associated osteosarcomas have been described, with just two being primarily osteolytic. We discuss a case of a patient with a humeral bone-infarct, who presented with a presumed benign pathological fracture of the humerus through the bone infarct. Subsequent imaging and biopsy showed that there was a malignant degeneration into a primarily osteolytic osteosarcoma. We review the patient's presentation, radiographic and histologic appearance of the osteosarcoma and discuss the epidemiology, surgical and non-surgical treatment and surveillance of bone-infarct-associated osteosarcomas.
Volume
10
Issue
6
First Page
2777
Last Page
2777
ISSN
2168-8184
Published In/Presented At
McDonald, M. D., Sadigh, S., Weber, K. L., & Sebro, R. (2018). A Rare Case of an Osteolytic Bone-infarct-associated Osteosarcoma: Case Report with Radiographic and Histopathologic Correlation, and Literature Review. Cureus, 10(6), e2777. https://doi.org/10.7759/cureus.2777
Disciplines
Anesthesiology | Medicine and Health Sciences
PubMedID
30112253
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article