Bradycardia leading to asystole during dexmedetomidine infusion in an 18 year-old double-lung transplant recipient.
Publication/Presentation Date
2-1-2010
Abstract
The case of an 18 year-old double-lung transplant recipient recovering from acute respiratory distress syndrome who developed repeated episodes of bradycardia and asystole (maximum duration: 10 sec) during dexmedetomidine administration is presented. Increased baseline vagal tone, paroxysmal coughing spells, and opioid administration were likely contributors to the episodes. Discontinuation of the drug restored regular sinus rhythm. Double-lung transplant recipients may be at especially increased risk for this phenomenon as a result of changes in the autonomic innervation of the heart.
Volume
22
Issue
1
First Page
45
Last Page
49
ISSN
1873-4529
Published In/Presented At
Zhang, X., Schmidt, U., Wain, J. C., & Bigatello, L. (2010). Bradycardia leading to asystole during dexmedetomidine infusion in an 18 year-old double-lung transplant recipient. Journal of clinical anesthesia, 22(1), 45–49. https://doi.org/10.1016/j.jclinane.2009.06.002
Disciplines
Anesthesiology | Medicine and Health Sciences
PubMedID
20206851
Department(s)
Department of Anesthesiology
Document Type
Article