Semi-automated mitral valve morphometry and computational stress analysis using 3D ultrasound.

Publication/Presentation Date

3-15-2012

Abstract

In vivo human mitral valves (MV) were imaged using real-time 3D transesophageal echocardiography (rt-3DTEE), and volumetric images of the MV at mid-systole were analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation, a compact representation of shape. The resulting MV models were loaded with physiologic pressures using finite element analysis (FEA). We present the regional leaflet stress distributions predicted in normal and diseased (regurgitant) MVs. Rt-3DTEE, semi-automated leaflet segmentation, 3D deformable modeling, and FEA modeling of the in vivo human MV is tenable and useful for evaluation of MV pathology.

Volume

45

Issue

5

First Page

903

Last Page

907

ISSN

1873-2380

Disciplines

Medicine and Health Sciences

PubMedID

22281408

Department(s)

Department of Medicine, Cardiology Division

Document Type

Article

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