Effect of acute unloading via head-up tilt on QTc prolongation in patients with ischemic or non-ischemic cardiomyopathy.

Publication/Presentation Date

2-1-2006

Abstract

Patients with advanced cardiomyopathy develop prolongations in ventricular myocyte action potential duration that are reflected by prolongations of QT intervals on surface electrocardiograms. Recent studies demonstrate that the placement of a left ventricular (LV) assist device, which induces profound cardiac decompression, acutely increases QT intervals within hours. The goal of this study was to use head-up tilt (HUT) to examine electrocardiographic responses to cardiac unloading in patients with cardiomyopathy. Surface electrocardiograms were analyzed during HUT in 21 patients with cardiomyopathy (ejection fraction

Volume

97

Issue

3

First Page

412

Last Page

415

ISSN

0002-9149

Disciplines

Medicine and Health Sciences

PubMedID

16442407

Department(s)

Department of Medicine, Cardiology Division

Document Type

Article

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