Corynebacterium Jeikeium Endocarditis: A Review of the Literature.

Publication/Presentation Date

9-1-2021

Abstract

Corynebacterium jeikeium is a gram-positive, aerobic, pleomorphic, nonspore forming bacillus, commonly present on the skin surface. Infective endocarditis secondary to C. jeikeium most commonly affects left-sided heart valves and has a higher likelihood to require valve replacement compared to other Corynebacterium endocarditis. C. jeikeium endocarditis is extremely difficult to treat as it is characteristically resistant to penicillin, cephalosporins and aminoglycosides, and sensitivity to quinolones, macrolides, tetracyclines and rifampin is variable. Despite treatment, mortality rates as high as 33% have been reported. We hereby review the literature regarding the epidemiology, diagnosis and treatment of this deadly microorganism.

Volume

29

Issue

5

First Page

259

Last Page

262

ISSN

1538-4683

Disciplines

Medicine and Health Sciences

PubMedID

32976125

Department(s)

Department of Medicine, Cardiology Division, Fellows and Residents

Document Type

Article

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