Development of diabetes mellitus post-renal transplantation is associated with poor short-term clinical outcomes.
Publication/Presentation Date
12-1-2003
Abstract
BACKGROUND: Although posttransplant diabetes mellitus (PTDM) is associated with poor long-term outcomes short-term outcomes are not well studied in renal transplant recipients (RTRs).
METHODS: RTRs between January 1999 and December 2000 (n = 181) stratified according to the occurrence of diabetes mellitus (DM), namely, non-DM (n = 72), previous DM (n = 88), and PTDM (n = 21) were compared for infections, hospital readmissions, and graft rejections during the first 6 months posttransplantation.
RESULTS: PTDM showed patients affected by a significantly higher rate of infections (57.1% vs 29.2%) and recurrent infections (28.5% vs 11.1%) compared to non-DM and a trend toward an increase compared to previous DM. PTDM patients had a significantly higher incidence of multiple readmissions compared to both previous DM (52.4% vs 20.5%) and non-DM (52.4% vs 23.6%). Subjects with PTDM showed a significantly higher occurrence of rejection (28.6% vs 9.1%) and recurrent rejection (14.3% vs 2.3%) than previous DM and a greater trend compared to non-DM.
CONCLUSION: PTDM is associated with poorer short-term outcomes than either non-DM or previous DM.
Volume
35
Issue
8
First Page
2916
Last Page
2918
ISSN
0041-1345
Published In/Presented At
Saleem, T. F., Cunningham, K. E., Hollenbeak, C. S., Alfrey, E. J., & Gabbay, R. A. (2003). Development of diabetes mellitus post-renal transplantation is associated with poor short-term clinical outcomes. Transplantation proceedings, 35(8), 2916–2918. https://doi.org/10.1016/j.transproceed.2003.10.068
Disciplines
Community Health and Preventive Medicine | Health Services Research | Medicine and Health Sciences
PubMedID
14697937
Department(s)
Department of Community Health and Health Studies
Document Type
Article