High-volume centers achieve superior outcomes in left ventricular assist device explant-heart transplantation.
Publication/Presentation Date
2-1-2026
Abstract
BACKGROUND: Left ventricular assist device
METHODS: Adult patients who underwent LVAD explantation with OHT between 2011 and 2024 were identified in the Organ Procurement and Transportation Network/United Network for Organ Sharing registry. Using a rank-order method based on surgical volume, centers were stratified as either high volume or low volume. The primary outcome was 1-year survival; secondary outcomes included graft failure, ischemic time, dialysis, stroke, and hospital length of stay. Kaplan-Meier and Cox regression analyses were performed to assess survival and predictors of mortality.
RESULTS: A total of 2863 patients across 121 centers were analyzed. Eight high-volume centers performed 31.3% (897 cases) of all LVAD explant-OHTs. Baseline characteristics, including heart failure etiology and LVAD device type, were similar in the 2 groups. High-volume centers demonstrated decreased ischemic time (mean, 3.1 ± 1.3 hours vs 3.5 ± 1.4 hours;
CONCLUSIONS: High-volume centers were associated with superior survival and improved perioperative outcomes following LVAD explant-OHT.
Volume
29
First Page
101524
Last Page
101524
ISSN
2666-2736
Published In/Presented At
McGeoch, C. L. B., Rust, C. J., Kodimerla, R., El Sammak, S., Mylonas, K. S., Naqvi, H., Randhawa, S. S., Tang, A., Halkos, M. E., Bishawi, M. M., Daneshmand, M. A., & Chan, J. L. (2025). High-volume centers achieve superior outcomes in left ventricular assist device explant-heart transplantation. JTCVS open, 29, 101524. https://doi.org/10.1016/j.xjon.2025.10.036
Disciplines
Medicine and Health Sciences
PubMedID
41960050
Department(s)
Medical Education
Document Type
Article