The impact of marijuana use on postoperative outcomes in reduction mammaplasty: Risks, complications, and considerations.

Publication/Presentation Date

5-10-2026

Abstract

BACKGROUND: The legalization and social acceptance of marijuana in the United States has led to a significant increase in its use. However, there is a paucity of data surrounding the effect of marijuana on surgical outcomes, posing challenges for risk stratification and perioperative management in plastic surgery. This study aimed to evaluate the relationship between marijuana consumption and postoperative outcomes in patients undergoing reduction mammaplasty (RM).

METHODS: A multicenter retrospective analysis was conducted to compare the outcomes in patients who underwent RM between 2019 and 2024. Patients were stratified based on marijuana use. The primary outcomes included postoperative complications. Multivariate logistic regression models were used to identify complications independently associated with marijuana use.

RESULTS: A total of 1243 RMs were analyzed. Marijuana users accounted for 20.2% of the procedures (n = 251 RMs). Marijuana users were younger (28.6 years; interquartile range [IQR], 13.5 vs. 38.3 years [IQR, 22.5]; p < 0.001) and had higher rates of tobacco use (16.3% vs. 10.3%; p = 0.010). However, marijuana use was independently associated with increased risk of hematoma formation (3.2% vs. 1.0%; p = 0.010; odds ratio [OR], 2.972; p = 0.039) and delayed wound healing (12.8% vs. 8.3%; p = 0.028; OR, 1.946; p = 0.018).

CONCLUSION: Perioperative marijuana use is associated with an increased risk of hematoma formation and delayed wound healing in RM patients. These findings underscore the need for standardized perioperative screening and counseling protocols regarding marijuana use.

Volume

118

First Page

146

Last Page

152

ISSN

1878-0539

Disciplines

Medicine and Health Sciences

PubMedID

42202559

Department(s)

Medical Education

Document Type

Article

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