Effect of Dextrose Cross-Linked Glutaraldehyde Hydrogel on Wound Healing Activity.
Publication/Presentation Date
4-1-2024
Abstract
Dextrose cross-linked glutaraldehyde hydrogels are effective and promising drug delivery candidates. The addition of chitosan with dextrose resulted in the polymerization of material which resulted in the production of a gel-like structure that was highly viscous and had gelling properties. A swelling and absorption assay was conducted on the hydrogel. The dextrose cross-linked hydrogel has a higher absorption potential for distilled water followed by PBS and the least absorption was observed in the ethanol. Dextrose cross-linked hydrogel favors solubility in distilled water as compared to other solvents. The amoxicillin release by the dextrose cross-linked hydrogel was then tested. The result from drug release demonstrates that the dextrose cross-linked hydrogel released more than 55% of the amoxicillin in 2 hours and the remaining portion of the drug remaining. Therefore, it has a slow drug-release property, and it can be used for further wound-healing studies.
Volume
16
Issue
Suppl 2
First Page
1195
Last Page
1195
ISSN
0976-4879
Published In/Presented At
Senthil, K., Kalpana, R., & Kumar, V. (2024). Effect of Dextrose Cross-Linked Glutaraldehyde Hydrogel on Wound Healing Activity. Journal of pharmacy & bioallied sciences, 16(Suppl 2), S1195–S1197. https://doi.org/10.4103/jpbs.jpbs_531_23
PubMedID
38882750
Department(s)
Administration and Leadership
Document Type
Article