How we measure hypoglossal nerve stimulator outcome matters: titration vs single amplitude efficacy sleep studies.

Publication/Presentation Date

1-1-2025

Abstract

STUDY OBJECTIVES: Hypoglossal nerve stimulator (HGNS) is a common treatment for obstructive sleep apnea. Objective assessment of HGNS efficacy measures apnea-hypopnea index (AHI) by multiamplitude titration polysomnography (tPSG) and/or a single amplitude, full-night type 3 home sleep study (eHST). Both tests have been used to determine efficacy despite significantly different protocols. This project's aim was to determine differences in objective outcomes in HGNS patients who underwent both tPSG and eHST postoperatively.

METHODS: Data from 379 consecutive HGNS patients were retrospectively reviewed. Inclusion requirements were a preoperative sleep study, a postoperative tPSG, and then an eHST, which at our institution is a type 3 home study. AHI mean and differences were calculated. Wilcoxon rank sum tests were used to analyze differences between tPSG and eHST. Sher

RESULTS: Ultimately 61 patients met inclusion criteria with an average preoperative AHI = 33.2 events/h. When comparing the patient's tPSG vs eHST, tPSG AHI was significantly lower (AHI = 8.8 events/h vs AHI = 17.6 events/h; respectively,

CONCLUSIONS: HGNS patient's postoperative tPSG AHI was significantly lower than their eHST outcome. This work highlights the importance of reporting the type of postoperative study used in evaluating HGNS efficacy and the need for single amplitude, full-night studies to assess HGNS efficacy more accurately.

CITATION: Kaffenberger TM, Sina EM, Hambach B, et al. How we measure hypoglossal nerve stimulator outcome matters: titration vs single amplitude efficacy sleep studies.

Volume

21

Issue

1

First Page

47

Last Page

53

ISSN

1550-9397

Disciplines

Education | Medical Education

PubMedID

39167433

Department(s)

Department of Education

Document Type

Article

Link to Full Text

Share

COinS