Neural signaling contributes to heart formation and growth in the invertebrate chordate,
Publication/Presentation Date
5-2-2025
Abstract
Neurons contribute to the complex interplay of signals that mediate heart development and homeostasis. Although a limited set of studies suggest that neuronal peptides impact vertebrate heart growth, the specific contributions of these peptides to cardiomyocyte progenitor differentiation or proliferation have not been elucidated. Here we show that the neuropeptide tachykinin along with canonical Wnt signaling regulate cardiomyocyte progenitor proliferation in the chordate model
ISSN
2692-8205
Published In/Presented At
Gruner, H. N., Pickett, C. J., Bao, J. Y., Garcia, R., Hozumi, A., Scully, T., Ning, S., Gao, M., Bautista, G., Maze, K., Lim, K., Osugi, T., Collins-Doijode, M., Cairns, O., Levis, G., Chen, S. Y., Gong, T., Satake, H., Moshe-Klein, A., Gigante, E. D., … Davidson, B. (2025). Neural signaling contributes to heart formation and growth in the invertebrate chordate, Ciona robusta. bioRxiv : the preprint server for biology, 2025.04.28.651085. https://doi.org/10.1101/2025.04.28.651085
Disciplines
Education | Medical Education
PubMedID
40654768
Department(s)
Department of Education
Document Type
Article