Modeling Bone Marrow Progenitor Cell Differentiation and Susceptibility to HIV-1 Infection.
Publication/Presentation Date
1-1-2014
Abstract
Human immunodeficiency virus type 1 (HIV-1) infection of the monocytic lineage is involved in the pathologic events associated with AIDS and HIV-1-associated dementia (HAD). Hematopoietic progenitor cells (HPCs) within the bone marrow are refractile to HIV-1 infection, while their progeny of the monocyte-macrophage lineage are susceptible. Previous studies, using phorbol-myristate-acetate (PMA) as a differentiating agent, have suggested that the CD34
Volume
1
Issue
2
First Page
00009
Last Page
00009
ISSN
2373-4442
Published In/Presented At
Alexaki, A., Quiterio, S. J., Nonnemacher, M. R., Shah, S., Liu, Y., Banerjee, A., Li, L., Passic, S., Pirrone, V., Kilareski, E., Petrovas, C., & Wigdahl, B. (2014). Modeling Bone Marrow Progenitor Cell Differentiation and Susceptibility to HIV-1 Infection. MOJ immunology, 1(2), 00009–9. https://doi.org/10.15406/moji.2014.01.00009
Disciplines
Medicine and Health Sciences
PubMedID
26229980
Department(s)
Department of Emergency Medicine
Document Type
Article