Treatment of toad venom poisoning with digoxin-specific Fab fragments.
Publication/Presentation Date
11-1-1996
Abstract
Toxicity from toad venom poisoning is similar to digoxin toxicity and carries a high mortality rate. We report on six previously healthy men who developed vomiting and bradycardia after ingesting a purported topical aphrodisiac. Each patient had positive apparent digoxin levels and the first four patients died of cardiac dysrhythmias. The last two patients recovered following treatment with digoxin Fab fragments. We analyzed samples of the purported aphrodisiac and found that it was identical to Chan Su, a Chinese medication made from toad venom. To our knowledge, this is the first reported use of digoxin Fab fragments to treat toad venom poisoning.
Volume
110
Issue
5
First Page
1282
Last Page
1288
ISSN
0012-3692
Published In/Presented At
Brubacher, J. R., Ravikumar, P. R., Bania, T., Heller, M. B., & Hoffman, R. S. (1996). Treatment of toad venom poisoning with digoxin-specific Fab fragments. Chest, 110(5), 1282–1288. https://doi.org/10.1378/chest.110.5.1282
Disciplines
Medicine and Health Sciences
PubMedID
8915235
Department(s)
Department of Emergency Medicine
Document Type
Article