CRH Affects the Phenotypic Expression of Sepsis-Associated Virulence Factors by
Publication/Presentation Date
1-1-2017
Abstract
Sepsis is a life-threatening health condition caused by infectious pathogens of the respiratory tract, and accounts for 28-50% of annual deaths in the US alone. Current treatment regimen advocates the use of corticosteroids as adjunct treatment with antibiotics, for their broad inhibitory effect on the activity and production of pro-inflammatory mediators. However, despite their use, corticosteroids have not proven to be able to reverse the death incidence among septic patients. We have previously demonstrated the potential for neuroendocrine factors to directly influence
Volume
7
First Page
263
Last Page
263
ISSN
2235-2988
Published In/Presented At
Ngo Ndjom, C. G., Kantor, L. V., & Jones, H. P. (2017). CRH Affects the Phenotypic Expression of Sepsis-Associated Virulence Factors by Streptococcus pneumoniae Serotype 1 In vitro. Frontiers in cellular and infection microbiology, 7, 263. https://doi.org/10.3389/fcimb.2017.00263
Disciplines
Medicine and Health Sciences
PubMedID
28690980
Department(s)
Department of Emergency Medicine
Document Type
Article