End Points of Sepsis Resuscitation.
Publication/Presentation Date
2-1-2017
Abstract
Resuscitation goals for the patient with sepsis and septic shock are to return the patient to a physiologic state that promotes adequate end-organ perfusion along with matching metabolic supply and demand. Ideal resuscitation end points should assess the adequacy of tissue oxygen delivery and oxygen consumption, and be quantifiable and reproducible. Despite years of research, a single resuscitation end point to assess adequacy of resuscitation has yet to be found. Thus, the clinician must rely on multiple end points to assess the patient's overall response to therapy. This review will discuss the role and limitations of central venous pressure (CVP), mean arterial pressure (MAP), and cardiac output/index as macrocirculatory resuscitation targets along with lactate, central venous oxygen saturation (ScvO
Volume
35
Issue
1
First Page
93
Last Page
107
ISSN
1558-0539
Published In/Presented At
Greenwood, J. C., & Orloski, C. J. (2017). End Points of Sepsis Resuscitation. Emergency medicine clinics of North America, 35(1), 93–107. https://doi.org/10.1016/j.emc.2016.09.001
Disciplines
Medicine and Health Sciences
PubMedID
27908340
Department(s)
Department of Emergency Medicine
Document Type
Article