Disorders of the Autonomic Nervous System after Hemispheric Cerebrovascular Disorders: An Update.
Publication/Presentation Date
10-2015
Abstract
Autonomic and cardiac dysfunction may occur after vascular brain injury without any evidence of primary heart disease. During acute stroke, autonomic dysfunction, for example, elevated arterial blood pressure, arrhythmia, and ischemic cardiac damage, has been reported, which may hinder the prognosis. Autonomic dysfunction after a stroke may involve the cardiovascular, respiratory, sudomotor, and sexual systems, but the exact mechanism is not fully understood. In this review paper, we will discuss the anatomy and physiology of the autonomic nervous system and discuss the mechanism(s) suggested to cause autonomic dysfunction after stroke. We will further elaborate on the different cerebral regions involved in autonomic dysfunction complications of stroke. Autonomic nervous system modulation is emerging as a new therapeutic target for stroke management. Understanding the pathogenesis and molecular mechanism(s) of parasympathetic and sympathetic dysfunction after stroke will facilitate the implementation of preventive and therapeutic strategies to antagonize the clinical manifestation of autonomic dysfunction and improve the outcome of stroke.
Volume
8
Issue
4
First Page
43
Last Page
52
ISSN
1941-5893
Published In/Presented At
Al-Qudah, Z. A., Yacoub, H. A., & Souayah, N. (2015). Disorders of the Autonomic Nervous System after Hemispheric Cerebrovascular Disorders: An Update. Journal Of Vascular And Interventional Neurology,8(4), 43-52.
Disciplines
Emergency Medicine
PubMedID
26576215
Department(s)
Department of Emergency Medicine, Department of Emergency Medicine Faculty
Document Type
Article