Tricyclic antidepressant toxicity treated with massive sodium bicarbonate.
Publication/Presentation Date
11-1-2009
Abstract
Tricyclic antidepressant (TCA) morbitity is primarily due to cardiac arrhythmias and hypotension, which become more refractory to treatment as acidosis progresses (Ann Emerg Med. 1985;14:1-9; Clin Toxicol. 2007;45:203-233; Flomenbaum N, Goldfrank L, Hoffman R, et al. Goldfrank's toxicologic emergencies. 8th ed. McGraw-Hill Companies, Inc, 2006). Early recognition and aggressive treatment are necessary for patient survival.
Volume
27
Issue
9
First Page
3
Last Page
7
ISSN
1532-8171
Published In/Presented At
Pierog JE, Kane KE, Kane BG, Donovan JW, Helmick T. Tricyclic antidepressant toxicity treated with massive sodium bicarbonate. Am J Emerg Med. 2009 Nov;27(9):1168.e3-7. doi: 10.1016/j.ajem.2008.11.026. PMID: 19931778.
Disciplines
Medicine and Health Sciences
PubMedID
19931778
Department(s)
Department of Emergency Medicine
Document Type
Article
COinS