Injectable Self-Assembling Peptide Hydrogels for
Publication/Presentation Date
4-1-2018
Abstract
The fabrication of extracellular matrix-mimic hydrogels that can nurture and direct differentiation of embryonic stem cells is an important target for pattern-printed tissue replacement. Another desirable feature for such materials is their ability to be injected and recover their rheological features post-injection, allowing for facile non-invasive implantation. In this report, we demonstrate the ability of a self-assembling peptide hydrogel to support the culture of embryonic stem cells with the potential to direct differentiation. We also show that we can write a functional tissue replacement with a predetermined pattern using our formulation. Our results may lead to
Volume
14
Issue
4
First Page
802
Last Page
807
ISSN
1550-7033
Published In/Presented At
Hitscherich, P., Nguyen, P. K., Kannan, A., Chirayath, A., Anur, S., Sarkar, B., Lee, E. J., & Kumar, V. A. (2018). Injectable Self-Assembling Peptide Hydrogels for Tissue Writing and Embryonic Stem Cell Culture. Journal of biomedical nanotechnology, 14(4), 802–807. https://doi.org/10.1166/jbn.2018.2583
Disciplines
Medicine and Health Sciences
PubMedID
31352954
Department(s)
Department of Emergency Medicine, Department of Emergency Medicine Residents, Fellows and Residents
Document Type
Article