Anti-Cancer Treatment Strategies in the Older Population: Time to Test More?
Publication/Presentation Date
4-15-2021
Abstract
Aging is a well-recognized risk factor for the development of cancer. The incidence of new cancer diagnoses has increased globally given the rising senior population. Many hypotheses for this increased risk have been postulated over decades, including increased genetic and epigenetic mutations and the concept of immunosenescence. The optimal treatment strategies for this population with cancer are unclear. Older cancer patients are traditionally under-represented in clinical trials developed to set the standard of care, leading to undertreatment or increased toxicity. With this background, it is crucial to investigate new opportunities that belong to the most recent findings of an anti-cancer agent, such as immune-checkpoint inhibitors, to manage these daily clinical issues and eventually combine them with alternative administration strategies of antiblastic drugs such as metronomic chemotherapy.
Volume
6
Issue
2
First Page
1147
Last Page
1147
ISSN
2308-3417
Published In/Presented At
Tralongo, A. C., Fratamico, R. S., Russo, C., Sbrana, A., Antonuzzo, A., & Danova, M. (2021). Anti-Cancer Treatment Strategies in the Older Population: Time to Test More?. Geriatrics (Basel, Switzerland), 6(2), 42. https://doi.org/10.3390/geriatrics6020042
Disciplines
Medicine and Health Sciences
PubMedID
33921136
Department(s)
Department of Medicine
Document Type
Article