Relapsed Multiple Myeloma Presenting as Intracranial Plasmacytoma and Malignant Pericardial Effusion following Recent Allogeneic Stem Cell Transplantation.

Authors

• Jonathan Pan
• Jason Chen
• Joanne Filicko
• Dolores Grosso
• Michelle Nagurney
• Onder Alpdogan
• Neal Flomenberg

Publication/Presentation Date

1-1-2017

Abstract

Although rare, both central nervous system and pericardial involvement of myeloma have been well described in the literature. Their simultaneous occurrence in relapsed disease, however, has not been previously reported. This case describes a 54-year-old female who was treated for high-risk multiple myeloma with multiregimen chemotherapy and allogeneic hematopoietic stem cell transplantation. Four months after transplant, she was found to have relapsed disease manifesting as an extraosseous, intracranial plasmacytoma and simultaneous malignant pericardial effusion. Her disease characteristics, treatment course, radiologic and pathologic findings are described in detail, and we review the previous literature to determine the various aspects of her disease that may have contributed to her aggressive clinical course.

Volume

10

Issue

2

First Page

582

Last Page

587

ISSN

1662-6575

Published In/Presented At

Pan, J., Chen, J., Filicko, J., Grosso, D., Nagurney, M., Alpdogan, O., & Flomenberg, N. (2017). Relapsed Multiple Myeloma Presenting as Intracranial Plasmacytoma and Malignant Pericardial Effusion following Recent Allogeneic Stem Cell Transplantation. Case reports in oncology, 10(2), 582–587. https://doi.org/10.1159/000478001

Disciplines

Medicine and Health Sciences

PubMedID

28868016

Department(s)

Hematology-Medical Oncology Division

Document Type

Article