Synchronous Low-Grade Central Osteosarcoma and Ewing Sarcoma: A Rare Case Report.

Authors

• Daniel Christensen
• Jeffrey A Belair
• Atrayee BasuMallick
• Scot A Brown
• Michael Klein
• Wei Jiang

Publication/Presentation Date

2-1-2025

Abstract

A 23-year-old female patient presented with radicular back pain, perineal numbness, and urinary retention. The patient was diagnosed with cauda equina syndrome and magnetic resonance imaging (MRI) of the spine revealed an enhancing osseous lumbar lesion causing severe central stenosis. A core needle biopsy of the lumbar spine showed microscopic features compatible with a small round blue cell tumor. CD99 and FLI1 were positive in the tumor cells. Next-generation sequencing demonstrated a

Volume

33

Issue

1

First Page

131

Last Page

137

ISSN

1940-2465

Published In/Presented At

Christensen D, Belair JA, BasuMallick A, Brown SA, Klein M, Jiang W. Synchronous Low-Grade Central Osteosarcoma and Ewing Sarcoma: A Rare Case Report. Int J Surg Pathol. 2025 Feb;33(1):131-137. doi: 10.1177/10668969241239675. Epub 2024 Mar 20. PMID: 38504661.

Disciplines

Medicine and Health Sciences

PubMedID

38504661

Department(s)

Hematology-Medical Oncology Division

Document Type

Article