Pancreatic cancer.
Publication/Presentation Date
12-1-2000
Abstract
Optimal therapy for pancreatic adenocarcinoma requires surgical removal with tumor-free margins. Superior outcomes have been reported for high-volume centers incorporating a multidisciplinary approach. Postoperative ("adjuvant") chemotherapy and radiation should be considered in patients with successfully resected primary tumors. Combined modality treatment with chemotherapy and radiation should be considered for locally advanced, unresectable tumors. Gemcitabine can provide symptom relief and a modest improvement in survival for patients with metastatic disease. Strict attention to relief of symptoms such as pain, depression, anorexia/cachexia, and jaundice is essential in all patients with pancreatic cancer. All patients with pancreatic cancer should be encouraged to enter clinical trials of new therapies, given that long-term survival for all stages remains poor.
Volume
1
Issue
5
First Page
375
Last Page
386
ISSN
1527-2729
Published In/Presented At
Cohen, S. J., Pinover, W. H., Watson, J. C., & Meropol, N. J. (2000). Pancreatic cancer. Current treatment options in oncology, 1(5), 375–386. https://doi.org/10.1007/s11864-000-0065-2
Disciplines
Medicine and Health Sciences
PubMedID
12057145
Department(s)
Hematology-Medical Oncology Division
Document Type
Article