Associations between neighborhood disadvantage, cannabis use, and patient-reported outcomes among patients with cancer.

Publication/Presentation Date

6-1-2026

Abstract

INTRODUCTION: Cannabis use is proliferating among oncological populations. However, research is limited on whether cannabis routes and sources are associated with neighborhood disadvantage and whether it moderates the relationship between neighborhood disadvantage and patient-reported outcomes (PROs). This analysis evaluates the relationship between neighborhood disadvantage and cannabis source and route, and their association with PROs.

METHODS: Analyses included 106 patients with cancer from varying levels of neighborhood disadvantage. Logistic regressions tested the association of neighborhood disadvantage with cannabis source (i.e., regulated vs. unregulated) and route (i.e., inhaled vs. consumed/other formulations). Multilevel regressions tested the association of neighborhood disadvantage with PROs (e.g., anxiety, depression, sleep quality, pain, quality of life) and moderation by cannabis variables.

RESULTS: Neighborhood disadvantage did not uniquely predict cannabis source or route (

CONCLUSION: Although the composite index of neighborhood disadvantage was not associated with cannabis use or PROs, our data suggest that income and cannabis route may be key factors associated with health disparities among patients with cancer.

Volume

19

First Page

100449

Last Page

100449

ISSN

2772-7246

Disciplines

Medicine and Health Sciences

PubMedID

42256669

Department(s)

Hematology-Medical Oncology Division

Document Type

Article

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