Impact of Using Blood Warmer During Continuous Kidney Replacement Therapy in Patients With Acute Kidney Injury.

Publication/Presentation Date

4-1-2024

Abstract

PURPOSE: We investigated the impact of blood warmer use on hypotensive episodes in patients with acute kidney injury (AKI) receiving continuous kidney replacement therapy (CKRT).

MATERIALS AND METHODS: We included patients with AKI undergoing CKRT between January 1, 2012, and January 1, 2021, at a tertiary academic hospital. Hypotensive episodes were defined as mean arterial pressure (MAP) < 60 mm Hg or a decrease in MAP by ≥10 mm Hg, systolic blood pressure (SBP) <  90 mm Hg or a decrease in SBP by ≥20 mm Hg, or increased vasopressor requirement. These were analyzed by Poisson regression with repeated-measures analysis of variance using generalized estimation equation.

RESULTS: There were 669 patients with AKI that required CKRT. Use of blood warmer on first day of CKRT was in 324 (48%) patients. Incidence rate ratio of hypotensive episodes during the first 24-h of CKRT in patients where a blood warmer was used was 1.06 (95% confidence interval [CI]: 0.98-1.13) compared to those where blood warmer was not used. This did not change in adjusted model. Overall, the within-subject effect of temperature on hypotensive episodes showed that higher temperature was associated with fewer episodes (0.94, 95% CI: 0.9-0.99 per 10 degrees increase,

CONCLUSION: Blood rewarming was not associated with hypotensive episodes during CKRT.

Volume

39

Issue

4

First Page

387

Last Page

394

ISSN

1525-1489

Disciplines

Medicine and Health Sciences

PubMedID

37885206

Department(s)

Department of Medicine

Document Type

Article

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