Sarcoidosis Presenting as Acute Respiratory Distress Syndrome.

Publication/Presentation Date

1-1-2018

Abstract

Sarcoidosis is a multisystem granulomatous disease of unknown origin. It typically involves the lungs and mediastinal lymph nodes in a chronic fashion. However, acute syndrome has been reported possibly in response to systemic release of proinflammatory cytokines. Acute pulmonary manifestations, especially acute respiratory failure or acute respiratory distress syndrome, remain extremely uncommon in individuals without a prior diagnosis. We present the case of a 41-year-old African American female, who presented with ARDS. An extensive workup into the cause of her illness remained negative, and she subsequently succumbed to her illness. A diagnosis of sarcoidosis was made upon autopsy, after exclusion of other granulomatous illness. The case highlights the need to consider this uncommon diagnosis in patients with unexplained ARDS to guide therapy.

Volume

2018

First Page

6465180

Last Page

6465180

ISSN

1687-9627

Disciplines

Medicine and Health Sciences

PubMedID

30675164

Department(s)

Department of Medicine

Document Type

Article

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