Idiosyncratic Drug Reaction: A Rare Mechanism of Acute Tylenol Toxicity.
Publication/Presentation Date
11-8-2019
Abstract
Acetaminophen (APAP) is perhaps the most commonly used drug both inside and outside the hospital due to its relative safety and over-the-counter availability. Despite its safety, it can cause drug-related side effects, especially acute liver injury that can be unpredictable. Additionally, due to its variable, delayed and nonspecific symptomatology, it can pose a significant diagnostic challenge. Due to potential reversibility with an antidote and adverse outcome related to liver failure, timely recognition and treatment is key in suspected toxicity. Here we present a case of a young female who presented for the evaluation of seizure and found to have APAP-related liver failure with only 2 g of APAP taken over two days duration.
Volume
11
Issue
11
First Page
6099
Last Page
6099
ISSN
2168-8184
Published In/Presented At
Raza, A., Chan, V., & Atiq, M. U. (2019). Idiosyncratic Drug Reaction: A Rare Mechanism of Acute Tylenol Toxicity. Cureus, 11(11), e6099. https://doi.org/10.7759/cureus.6099
Disciplines
Medicine and Health Sciences
PubMedID
31886040
Department(s)
Department of Medicine
Document Type
Article