Warfarin Failure in a Patient With Chronic Thromboembolic Pulmonary Hypertension: A Case Report and Literature Review.
Publication/Presentation Date
7-1-2022
Abstract
Chronic thromboembolic pulmonary hypertension (CTEPH) is a form of pulmonary hypertension caused by chronic venous thromboembolism (VTE). Venous thromboembolism (VTE) manifests as deep vein thrombosis (DVT), progressing to pulmonary embolism (PE). Pulmonary endarterectomy (PEA) is the preferred therapeutic option as it provides vascular disobliteration. Long-term anticoagulation with warfarin or direct oral anticoagulants (DOACs) is recommended for patients at risk for recurrent DVT in poor surgical candidates. However, treatment failure remains a concern. We present a patient who had VTE despite long-term anticoagulation with warfarin who had failed treatment and developed VTE with a therapeutic dilemma to continue anticoagulation despite supratherapeutic international normalized ratio (INR).
Volume
14
Issue
7
First Page
27007
Last Page
27007
ISSN
2168-8184
Published In/Presented At
Dolkar, T., Chaudry, A., Salauddin, F., Nway, N., Kadakia, N., Kalavar, M., & Dogar, M. H. (2022). Warfarin Failure in a Patient With Chronic Thromboembolic Pulmonary Hypertension: A Case Report and Literature Review. Cureus, 14(7), e27007. https://doi.org/10.7759/cureus.27007
Disciplines
Medicine and Health Sciences
PubMedID
35989750
Department(s)
Department of Medicine
Document Type
Article