Idiopathic Retinal Vasculitis, Aneurysms, and Neuro-Retinitis. Retinal Vasculitis Study.
Publication/Presentation Date
7-1-1995
Abstract
PURPOSE: The authors describe the clinical feature of ten patients with a new syndrome characterized by the presence of retinal vasculitis, multiple macroaneurysms, neuro-retinitis, and peripheral capillary nonperfusion.
METHODS: The authors evaluated ten patients identified to have clinical features compatible with the syndrome of idiopathic retinal vasculitis, aneurysms and neuroretinits (IRVAN). Clinical examination findings, sequential funds photographs (when available), fluorescein angiograms, systemic investigations, response to therapy, and visual outcomes were reviewed.
RESULTS: Seven eyes of four patients sustained a marked decrease in visual acuity of 20/200 or worse. Visual loss was due to a combination of an exudative maculopathy and sequelae of retinal ischemia. Capillary nonperfusion was seen in all ten patients and was severe enough to warrant panretinal laser photocoagulation in six patients. Systemic investigations were uniformly noncontributory. Oral prednisone appears to have little beneficial effects on patients with this disorder.
CONCLUSIONS: Patients with IRVAN have characteristic retinal features that readily identify this syndrome. An increased awareness of this rare syndrome may help to identify sight-threatening complications at an earlier stage. The authors caution against extensive medical investigations.
Volume
102
Issue
7
First Page
1089
Last Page
1097
ISSN
0161-6420
Published In/Presented At
Chang, T. S., Aylward, G. W., Davis, J. L., Mieler, W. F., Oliver, G. L., Maberley, A. L., & Gass, J. D. (1995). Idiopathic retinal vasculitis, aneurysms, and neuro-retinitis. Retinal Vasculitis Study. Ophthalmology, 102(7), 1089-1097
Disciplines
Medical Sciences | Medicine and Health Sciences | Ophthalmology
PubMedID
9121757
Department(s)
Department of Medicine
Document Type
Article