Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup.

Authors

• Bernhard Dumoulin
• Jonathan Levinsohn
• Konstantin A Klötzer
• Chenyu Li
• Liran Mao
• Eunji Ha
• Samer Mohandes
• Thao Nguyen
• Luca Paruzzo
• Daigoro Hirohama
• Victoria Fang
• Vijay G Bhoj
• Hamideh Parhiz
• Magaiver Andrade-Silva
• Amin Abedini
• Andi Bergeson
• Daniel Traum
• Michael J May
• Klaus H Kaestner
• Marco Ruella
• Fiona Elizabeth McAllister
• A Ari Hakimi
• Mingyao Li
• Matthew Palmer
• E John Wherry
• Christopher A Hunter
• Michael Paul Cancro
• Katalin Susztak
• Nelson Kopyt DO, FASN, FACP, Lehigh Valley Health NetworkFollow

Publication/Presentation Date

4-29-2026

Abstract

Diabetic kidney disease (DKD), the leading cause of kidney failure, is marked by clinical and molecular heterogeneity, making therapeutic development exceedingly difficult

ISSN

1476-4687

Published In/Presented At

Dumoulin, B., Levinsohn, J., Klötzer, K. A., Li, C., Mao, L., Ha, E., Mohandes, S., Nguyen, T., Paruzzo, L., Hirohama, D., Fang, V., Bhoj, V. G., Parhiz, H., Andrade-Silva, M., Abedini, A., Bergeson, A., Traum, D., May, M. J., Kaestner, K. H., Ruella, M., … Susztak, K. (2026). Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup. Nature, 10.1038/s41586-026-10363-4. Advance online publication. https://doi.org/10.1038/s41586-026-10363-4

Disciplines

Medicine and Health Sciences

PubMedID

42056516

Department(s)

Department of Medicine

Document Type

Article