A noninvasive protocol for anterior temporal lobectomy.
Publication/Presentation Date
2-1-1992
Abstract
We report the results of a protocol for choosing candidates for temporal lobectomy using a standard battery of objective tests without intracranial electrodes. We assigned each test a level of importance, and an algorithm was used to determine whether temporal lobectomy could be performed. Fifty-one patients (total pool, 103 patients) met protocol requirements and had an anterior temporal lobectomy with a mean follow-up of 39.4 months (range, 21 to 64 months), most remaining on anticonvulsant therapy. Eighty percent are seizure free, 12% have less than 3 seizures per year or only nocturnal seizures, and 8% have greater than 80% reduction in seizure frequency. One-third of patients who failed protocol criteria did not have temporal lobe seizures when studied with intracranial electrodes. We analyzed and modified the algorithm after comparing these patients with others who were poor candidates for temporal lobectomy. We conclude that this protocol is effective and recommend using such an objective algorithm.
Volume
42
Issue
2
First Page
416
Last Page
422
ISSN
0028-3878
Published In/Presented At
Sperling, M. R., O'Connor, M. J., Saykin, A. J., Phillips, C. A., Morrell, M. J., Bridgman, P. A., French, J. A., & Gonatas, N. (1992). A noninvasive protocol for anterior temporal lobectomy. Neurology, 42(2), 416–422. https://doi.org/10.1212/wnl.42.2.416
Disciplines
Medicine and Health Sciences
PubMedID
1736176
Department(s)
Department of Medicine
Document Type
Article