Corpus callosotomy.
Publication/Presentation Date
8-1-2008
Abstract
Corpus callosotomy is a palliative surgical procedure that is suitable for some patients with intractable seizures who are not candidates for focal resective surgery. The rationale for this procedure is based on the hypothesis that the corpus callosum is a critical pathway for interhemispheric spread of epileptic activity. Efficacy and relatively low permanent morbidity in corpus callosotomy for medically intractable epilepsy have been demonstrated by more than six decades of experience. Callosotomy best ameliorates drop attacks (tonic and atonic seizures), though tonic-clonic, absence, and frontal lobe complex partial seizures often respond as well. In addition to seizure reduction, behavior and quality of life may improve. Hence, callosotomy is justified as a therapy for appropriate patients with intractable epilepsy.
Volume
13
Issue
2
First Page
271
Last Page
278
ISSN
1525-5069
Published In/Presented At
Asadi-Pooya, A. A., Sharan, A., Nei, M., & Sperling, M. R. (2008). Corpus callosotomy. Epilepsy & behavior : E&B, 13(2), 271–278. https://doi.org/10.1016/j.yebeh.2008.04.020
Disciplines
Medicine and Health Sciences
PubMedID
18539083
Department(s)
Department of Medicine
Document Type
Article