Long-term cardiac rhythm and repolarization abnormalities in refractory focal and generalized epilepsy.

Publication/Presentation Date

8-1-2012

Abstract

This prospective study evaluated 19 individuals with refractory focal or generalized epilepsy utilizing an implantable cardiac loop recorder. Recording averaged 15 months (range 12-19 months) in 18 patients and 1.5 months in one patient. A median of 37 seizures per patient (range 3-657) occurred, with 1,477 seizures total. Cardiac arrhythmias and repolarization abnormalities occurred frequently (in 42% of patients) in refractory epilepsy, particularly during generalized tonic-clonic and tonic seizures. Patients with Lennox-Gastaut syndrome may be at high risk for cardiac abnormalities.

Volume

53

Issue

8

First Page

137

Last Page

140

ISSN

1528-1167

Disciplines

Medicine and Health Sciences

PubMedID

22709423

Department(s)

Department of Medicine

Document Type

Article

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