Direct recordings of grid-like neuronal activity in human spatial navigation.

Authors

• Joshua Jacobs
• Christoph T Weidemann
• Jonathan F Miller
• Alec Solway
• John F Burke
• Xue-Xin Wei
• Nanthia Suthana
• Michael R Sperling
• Ashwini D Sharan
• Itzhak Fried
• Michael J Kahana

Publication/Presentation Date

9-1-2013

Abstract

Grid cells in the entorhinal cortex appear to represent spatial location via a triangular coordinate system. Such cells, which have been identified in rats, bats and monkeys, are believed to support a wide range of spatial behaviors. Recording neuronal activity from neurosurgical patients performing a virtual-navigation task, we identified cells exhibiting grid-like spiking patterns in the human brain, suggesting that humans and simpler animals rely on homologous spatial-coding schemes.

Volume

16

Issue

9

First Page

1188

Last Page

1190

ISSN

1546-1726

Published In/Presented At

Jacobs, J., Weidemann, C. T., Miller, J. F., Solway, A., Burke, J. F., Wei, X. X., Suthana, N., Sperling, M. R., Sharan, A. D., Fried, I., & Kahana, M. J. (2013). Direct recordings of grid-like neuronal activity in human spatial navigation. Nature neuroscience, 16(9), 1188–1190. https://doi.org/10.1038/nn.3466

Disciplines

Medicine and Health Sciences

PubMedID

23912946

Department(s)

Department of Medicine

Document Type

Article